Peptide Conjugated Dihydroazulene/Vinylheptafulvene Photoswitches in Aqueous Environment

Light-responsive molecules have seen a major advance in modulating biological functions recent years. Especially photoswitches are highly attractive building blocks due to the reversible nature of their light-mediated reactivity. They frequently used affect both properties small bioactive compounds and biomacromolecules if incorporated suitably. Despite success plethora applications, only limited set photochromic core structures is routinely employed large number couples under-investigated context. Broadening toolbox available modulate activity would open new avenues unlock full potential photoswitchable for studies. In this work, we explore photochemical thermal dihydroazulene/vinylheptafulvene couple as peptide conjugates aqueous environment.